Dr. Kui Hua – Senior Bioinformatician
Kui Hua is an Assistant Research Professor at the Cancer Research UK Cambridge Institute (CRUK-CI) and Chief Bioinformatician of the Spatial Profiling and Annotation Centre of Excellence (SPACE-lab). He earned his Ph.D. in the Department of Automation at Tsinghua University in 2021, followed by postdoctoral training with Dr John Marioni and Professor Greg Hannon at CRUK-CI and EMBL-EBI. Kui’s research sits at the interface of computational biology, spatial omics, statistical modelling, and artificial intelligence. He develops computational methods and platforms for the integrative and comparative analysis of cohort-level spatial multi-omic data, with a particular focus on understanding how cells coordinate to form tissues, organs, and complex organisms, and how these spatial relationships are altered during development, injury, disease, and cancer. His current work aims to move beyond descriptive analysis of individual samples towards scalable frameworks that can compare tissue organisation across patients, conditions, perturbations, and modalities. By combining spatial transcriptomics, proteomics, imaging, machine learning, and statistical modelling, his long-term goal is to uncover general principles of cellular organisation and communication, and to translate these insights into improved understanding of cancer biology and therapeutic response.
https://orcid.org/0000-0003-2228-7025
